AACC scientists identify new cardiac biomarker

Posted on by Kurt Jensen

Plus, get ready for high sensitivity cardiac Troponin assays in practice.

Laboratory medicine experts discovered a new lipid biomarker panel to detect heart failure with reduced ejection fraction (HFrEF) even before symptoms present, with "much greater certainty than standard tests for this condition," according to a January 5 press release from the American Association for Clinical Chemistry (AACC).

The January issue of the AACC's journal, Clinical Chemistry focuses on cardiovascular disease and features research reflecting a "growing understanding of the molecular signatures of heart disease," according to the press release, and a trend towards developing "more precise tests for the early diagnosis, monitoring, and targeted treatment."

The study in question identified three new cardiac lipid biomarkers, a cardiac lipid panel (CLP), which "significantly improved diagnostic performance" when combined with the current standard biomarker approach for diagnosing heart failure, NT-proBNP.

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Improving adherence to medications for heart failure: Medtronic says their CRT does it

Posted on by Kurt Jensen

Despite relatively few strong research studies supporting methodologies for improving adherence to medications for patients with heart failure, Medtronic's recent press release suggests their cardiac resynchronization therapy (CRT) implants might do the trick.

Medtronic accounced results of a retrospective analysis of administrative claims data of more than 4,500 patients with heart failure at the 2016 Heart Failure Society of America Scientific Meeting, Monday.

The analysis found that the number of patients "fully compliant" to a regimen of guideline-recommended medications "nearly doubled" at twelve months following CRT implants compared to those who did not receive implants.

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A revolution in chronic heart failure management and more in CV Directions Vol. 3, No. 1

Posted on by Kurt Jensen

This is the first and only FDA-approved heart failure monitoring solution proven to reduce heart failure hospital admissions when used by physicians to manage heart failure. And the reduction is significant— 28 percent within the first six months and 37 percent over 15 months demonstrated in a large randomized study...

Learn more about CardioMEMS, find strategies to improve case mix index, or build a learning community in your team through preceptorship—all inside the Alliance of Cardiovascular Professionals flagship, peer-reviewed publication, CV Directions.

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Is heart failure over-diagnosed? and other stories

Posted on by Kurt Jensen

Is heart failure over-diagnosed?

A common problem in elderly men, obstructive uropathy, can look a lot like heart failure.

When pulmonary edema is present, heart failure is often the "scapegoat" says Melissa Walton-Shirley, MD in a commentary on Medscape. Approaching heart failure with "an air of skepticism" might help.

I've seen a handful of obstructive uropathy cases masquerading as heart failure in elderly men in recent years. I shudder to think how many times I've missed it. I suspect that it's not just men who suffer. Some of our female patients with "diastolic dysfunction" and overflow incontinence seem to suffer from backpressure that finds its way into the pulmonary vasculature.

Melissa Walton-Shirley, MD
Read more on Medscape.

NYU Langone tests new transcatheter device.

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